Source | M.W. | 406.48 | CAS No. | 1062368-24-4 | |
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Structural Info | ![]() | ||||
Formulation | Powder | ||||
Reconstitution | Before reconstitution, werecommend a brief spin to drive down any material dislodged from the bottom ofthe tube. The compound is soluble inDMSO. | ||||
Stability | The powder is stable for atleast 2 year if stored at -20 °C. The dissolved compound is stable for at least 1 month at 4 °C, butshould be stored in aliquots at -20 °C for longer term. Protect from light. | ||||
Purity | Greater than 98% as determined by LC/MS analysis.LC/MS and/or NMR data available upon request. | ||||
Biological Activity | |||||
Country of Origin | USA |
A selectiveinhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2and ALK-3). Only weakly inhibits ALK-4,-5, and -7. 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinolineRef: Cuny, G.D., et al. Structure-activityrelationship study of bone morphogenetic protein (BMP) signaling inhibitors.Bioorg Med Chem Lett 18: 4388-92, 2008.
StemRD 是美国一家聚焦于尖端干细胞研究的公司,拥有蛋白表达和纯化方面的专利技术,使StemRD能够保证高效的生产那些用传统方法很难得到的重要干细胞因子。StemRD 拥有被美国FDA认证的可用于GMP生产治疗型多肽的设施。StemRD的实验室也拥有包括组织培养、细胞处理、超离心、超过滤、FPLC、HPLC和LC/MS等一系列先进设备。