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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Stemrd/SB431542, ALK-4, -5, -7 Inhibitor/10 mg/SB-010
产品编号:SB-010
市  场 价:¥2980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Stemrd
公      司:Stemrd
公司分类:
Stemrd/SB431542, ALK-4, -5, -7 Inhibitor/10 mg/SB-010
商品介绍
SourceM.W.384.39CAS No.301836-41-9
Structural Info4-(5-BENZOL[1,3]DIOXOL-5-YL-4-PYRLDIN-2-YL-1H-IMIDAZOL-2-YL)-BENZAMIDESB 431542
FormulationPowder
ReconstitutionBefore reconstitution, werecommend a brief spin to drive down any material dislodged from the bottom ofthe tube. The compound is soluble inDMSO.
StabilityThe powder is stable for atleast 2 year if stored at -20°C. The dissolved compound is stable for at least 1 month at 4 °C, butshould be stored in aliquots at -20 °C for longer term. Protect from light.
PurityGreater than 98% as determined by LC/MS analysis.LC/MS and/or NMR data available upon request.
Biological Activity
Country of OriginUSA

A selectiveinhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50= 94 nM), and the related ALK4 and ALK7.Ref: Lapinget al. Inhibition of transforming growth factor (TGF)-β1-inducedextracellular matrix with a novel inhibitor of the TGF-β type I receptor kinaseactivity: SB-431542. Mol.Pharmacol. 62 58, 2002. Inmanet al. SB-431542 is a potent and specific inhibitor of transforminggrowth factor-β superfamily type I activin receptor-like kinase (ALK) receptorsALK4, ALK5, and ALK7. Mol.Pharmacol. 62 65, 2002.

Product Sheet
品牌介绍

StemRD 是美国一家聚焦于尖端干细胞研究的公司,拥有蛋白表达和纯化方面的专利技术,使StemRD能够保证高效的生产那些用传统方法很难得到的重要干细胞因子。StemRD 拥有被美国FDA认证的可用于GMP生产治疗型多肽的设施。StemRD的实验室也拥有包括组织培养、细胞处理、超离心、超过滤、FPLC、HPLC和LC/MS等一系列先进设备。

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